Glycolysis/OXPHOS Assay Kit

Description

Adenosine triphosphate (ATP), synthesized by glycolysis and mitochondrial oxidative phosphorylation, is a crucial energy source for living cells. Many cancer cells produce ATP by glycolysis. However, recent studies have suggested that if glycolysis is suppressed in cancer cells, their ATP synthesis shifts to oxidative phosphorylation by enhancing mitochondrial function. It is expected that understanding these phenomena will be helpful for elucidation of the mechanism of anticancer drugs and will lead to the development of therapeutic strategies for cancer, neurodegenerative disease, and various diseases.

The Glycolysis/OXPHOS Assay Kit enables analysis of cellular glycolytic capacity, whether cells rely on glycolysis or oxidative phosphorylation for energy production, and metabolism shift by using inhibitors (Oligomycin and/or 2-DG).