(±)-Miconazole nitrate, 100 g

Key Features and Details

(±)-Miconazole Nitrate

SYNONYMS: 1-[2,4-Dichloro-ß-([2,4-dichlorobenzyl]oxy)phenethyl]imidazole nitrate salt; 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole nitrate salt; 1-[2,4-Dichloro-ß-([2,4-dichloro- benzyl]oxy]phenethyl]imidazole
CAS: # 75319-48-1
MOLECULAR FORMULA: C18H14Cl4N2O·HNO3
MOLECULAR WEIGHT: 479.135 g/mol
EC No: 245-256-6
MDL No: MFCD00058161
SKU 0215169380 Categories , , Tag

PRODUCT DESCRIPTION

(±)-Miconazole Nitrate

Application Notes

(±)-Miconazole Nitrate is used topically and by intravenous infusion. It is used to inhibit cytochrome P450 and to study automated luminescence-based cytochrome P450 profiling.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antifungal

SPECIFICATIONS
SKU: 0215169380
Base Catalog Number: 15169380
Alternate Names: 1-[2,4-Dichloro-ß-([2,4-dichlorobenzyl]oxy)phenethyl]imidazole nitrate salt; 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole nitrate salt; 1-[2,4-Dichloro-ß-([2,4-dichloro- benzyl]oxy]phenethyl]imidazole
Biochemical Physiological Actions : Miconazole interacts with 14-a demethylase, a cytochrome P-450 enzyme necessary for ergosterol biosynthesis. The inhibition of ergosterol results in increased cellular permeability causing leakage of cellular contents. Miconazole may also inhibit endogenous respiration, interact with phospholipids in the cell membrane, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and interfere with triglyceride and phospholipid biosynthesis.
CAS : # 75319-48-1
EC No : 245-256-6
Format : Powder
Hazard Statements : H302-H317
MDL No : MFCD00058161
Molecular Formula : C18H14Cl4N2O·HNO3
Molecular Weight : 479.135 g/mol
PPE : Dust mask, Eyeshields, Faceshields, Gloves
RTECS No : NI4771000
Safety Symbol : GHS07
Solubility : 26.3 [ug/mL]

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