Phorbol-12-myristate-13-acetate, >99%

Key Features and Details

Phorbol-12-Myristate-13-Acetate

SYNONYMS: Phorbol Acetate Myristate; Phorbol Monoacetate Monomyristate; PMA; 12-O-Tetradecanoylphorbol 13-acetate; 4,9,12,13,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate; TPA
CAS: # 16561-29-8
MOLECULAR FORMULA: C36H56O8
MOLECULAR WEIGHT: 616.836 g/mol
BEILSTEIN REGISTRY No.: 2407201
MDL No: MFCD00036736

PRODUCT DESCRIPTION

Phorbol-12-Myristate-13-Acetate Application Notes PMA activates Ca2+- ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells. Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. Key Applications Very Potent tumor promoter
SPECIFICATIONS
SKU: 02151864-CF
Base Catalog Number: 151864
Alternate Names: 151864
Beilstein Registration No : 2407201
Biochemical Physiological Actions : Potent tumor promoter; activates protein kinase C in vivo and in vitro.
CAS : # 16561-29-8
Hazard Statements : H315
MDL No : MFCD00036736
Melting Point : 162° F (NTP, 1992)
Molecular Formula : C36H56O8
Molecular Weight : 616.836 g/mol
PPE : Dust mask, Eyeshields, Gloves
Purity : 99%
RTECS No : QH4377000
Safety Symbol : GHS07
Solubility : Practically insoluble (NTP, 1992)
Vapor Pressure : 1.8X10-17 mm Hg at 25 deg C (est)

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