Fibronectin

Key Features and Details

Fibronectin

SYNONYMS: CIG; Cold insoluble globulin
CAS: # 86088-83-7
EC No: 289-149-2
MDL No: MFCD00131062

PRODUCT DESCRIPTION

Fibronectin Application Notes Fibronectin has been shown to stimulate the proliferation of rat osteoblasts in vitro; to induce odontoblast polarization and to regulate the differentiation of human dental pulp cells into odontoblasts. It has wide applications in cellular research into proliferation, differentiation, development and morphology. Precoating of glass, plastic and micro-carrier beads aids cell attachment, particularly those cell which are deficient in cell surface fibronectin. It has been reported that proteolytic digests of fibronectin are mitogenic for CH23 fibroblasts. Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. Key Applications Glycoproteins
SPECIFICATIONS
SKU: 02150025-CF
Base Catalog Number: 150025
Alternate Names: 150025
Biochemical Physiological Actions : Domains of fibronectin bind with collagen, fibrin, heparin, and specific cell membrane receptors. The most notable domain, Arg-Gly-Asp can be recognized by integrins and mediates cell adhesion. Fibronectin is also widely involved in interactions such as the attachment and migration of many cell types, cytoskeletal assembly, tyrosine phosphorylation, and metastasis.
CAS : # 86088-83-7
EC No : 289-149-2
Extinction Coefficient : E1%= 12.9 (280 nm in 8 M urea-0.2 M NaOH)(Lit.)
Format : Lyophilized powder
Isoelectric Point : 5.5 - 6.3 (Lit.)
MDL No : MFCD00131062
PPE : Eyeshields, Gloves, Respirator filter
Purity : =90%
Source : Bovine Plasma
Sterility : Sterile Filtered
Typical Working Concentration : 5-25 µg/mL (average is 10 µg/mL). Enrofloxacin is typically used for approximately 12 to 20 days in cell culture media with the media being changed every 3 to 4 days. Oral adminstration is typically given at 10 mg/kg; IV administration is typically given at 5 mg/kg.

© All rights reserved byJuniperlifesciences.com 2021

All logos and Trademarks are names the property of their respective owners.

Shopping Cart
Scroll to Top

Enquire

Login to your account
Login to your account