Orotic acid, monohydrate

Key Features and Details

Orotic Acid Monohydrate

SYNONYMS: 2,6-Dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid; Uracil-6-carboxylic acid; Whey factor; Animal galactose factor; Oropur; Orotyl; 6-Carboxy-2,4-dihydroxypyrimidine
CAS: # 50887-69-9
MOLECULAR FORMULA: C5H4N2O4 • H2O
MOLECULAR WEIGHT: 174.112 g/mol
BEILSTEIN REGISTRY No.: 7604036
MDL No: MFCD00149398
SKU 02102508-CF Categories , , Tag

PRODUCT DESCRIPTION

Orotic Acid Monohydrate Application Notes Orotic acid (OA) may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5'-phospho-a-d-ribose 1'-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5'-monophosphate (OMP). Orotic acid is used as a starting material for the potential commercial bioproduction of uridine 5'-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. OA may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis. Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. Key Applications Used in study of biosynthesis of pyrimidine nucleobases
SPECIFICATIONS
SKU: 02102508-CF
Base Catalog Number: 102508
Alternate Names: 102508
Beilstein Registration No : 7604036
CAS : # 50887-69-9
Format : Powder
Hazard Statements : H315-H319-H335
MDL No : MFCD00149398
Molecular Formula : C5H4N2O4 • H2O
Molecular Weight : 174.112 g/mol
PPE : Dust mask, Eyeshields, Gloves
Safety Symbol : GHS07
UV Visible Absorbance : ? max (water) 205 nm (280 nm) ± 5 nm

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