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1,1-Dimethylbiguanide hydrochloride
Key Features and Details
1,1-Dimethylbiguanide Hydrochloride
SYNONYMS: N,N-Dimethylimidodicarbonimidic diamine; 1,1-Dimethylbiguanide hydrochloride; DMGG; LA-6023; Metformin hydrochloride
CAS: #
1115-70-4
MOLECULAR FORMULA: C4H12ClN5
MOLECULAR WEIGHT: 165.625 g/mol
EC No: 214-230-6
MDL No: MFCD00012582
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PRODUCT DESCRIPTION
1,1-Dimethylbiguanide Hydrochloride
Application Notes
1,1-Dimethylbiguanide Hydrochloride has various medical uses such as in polycystic ovary syndrome, non-alcoholic fatty liver disease and diabetes mellitus type 2. It may also reduce weight gain in people taking atypical antipsychotics. 1,1-Dimethylbiguanide hydrochloride is suitable biguanide agent used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
An antidiabetic agent
SPECIFICATIONS
SKU: 02157805-CF
Base Catalog Number: 157805
Alternate Names: N,N-Dimethylimidodicarbonimidic diamine; 1,1-Dimethylbiguanide hydrochloride; DMGG; LA-6023; Metformin hydrochloride
Biochemical Physiological Actions
: 1,1-Dimethylbiguanide hydrochloride (Metformin) is an antidiabetic agent that reduces blood glucose levels and improves insulin sensitivity. Its metabolic effects, including the inhibition of hepatic gluconeogenesis, are mediated at least in part by activation of the LKB1-AMPK (AMP-activated protein kinase) pathway. Activation of this pathway also appears to be involved in the antiproliferative and proapoptotic actions of metformin in cancer cell lines.
CAS
: #
1115-70-4
EC No
: 214-230-6
Format
: Powder
Hazard Statements
: H302-H315-H319
MDL No
: MFCD00012582
Molecular Formula
: C4H12ClN5
Molecular Weight
: 165.625 g/mol
PPE
: Dust mask, Eyeshields, Gloves
RTECS No
: DU1800000
Safety Symbol
: GHS07
Solubility
: In water, 1.06X10+6 mg/L (miscible) at 25 deg C (est)
Vapor Pressure
: 7.58X10-5 mm Hg at 25 deg C (est)
