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2-Mercaptoethanol
Key Features and Details
2-Mercaptoethanol
SYNONYMS: ß-Mercaptoethanol; 2-Hydroxyethylmercaptan; BME; Thioethylene glycol; 2-Hydroxy-1-ethanethiol; Monothioethyleneglycol
CAS: #
60-24-2
MOLECULAR FORMULA: C2H6OS
MOLECULAR WEIGHT: 78.129 g/mol
BEILSTEIN REGISTRY No.: 773648
EC No: 200-464-6
MDL No: MFCD00004890
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PRODUCT DESCRIPTION
2-Mercaptoethanol
Application Notes
2-Merceptoethanol is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Solubilization of proteins
SPECIFICATIONS
SKU: 02190242-CF
Base Catalog Number: 190242
Alternate Names: ß-Mercaptoethanol; 2-Hydroxyethylmercaptan; BME; Thioethylene glycol; 2-Hydroxy-1-ethanethiol; Monothioethyleneglycol
Auto Ignition: 295°C
Beilstein Registration No
: 773648
Boiling Point
: 315 to 316° F at 742 mm Hg (decomposes) (NTP, 1992)
CAS
: #
60-24-2
Density
: 1.1143 at 68° F (NTP, 1992)
EC No
: 200-464-6
Flash Point
: 165° F (NFPA, 2010)
Format
: Liquid
Grade
: Standard
Hazard Statements
: H301-H310 + H330-H315-H317-H318-H410
MDL No
: MFCD00004890
Melting Point
: -148° F (NTP, 1992)
Molecular Formula
: C2H6OS
Molecular Weight
: 78.129 g/mol
PPE
: Faceshields, full-face respirator , Gloves, Goggles, respirator filter
Purity
: =98%
Refractive Index
: n20/D 1.500(lit.)
RTECS No
: KL5600000
Safety Symbol
: GHS05, GHS06, GHS09
Solubility
: greater than or equal to 100 mg/mL at 68° F (NTP, 1992)
Vapor Density
: 2.69 (NTP, 1992) (Relative to Air)
Vapor Pressure
: 1 mm Hg at 68° F (NTP, 1992)
