5-Fluorodeoxyuridine

Key Features and Details

5-Fluorodeoxyuridine

SYNONYMS: 2'-Deoxy-5-Fluorouridine; Floxuridine; 5-Fluoro-2'-deoxyuridine; FUDR; dFUR
CAS: # 50-91-9
MOLECULAR FORMULA: C9H11FN2O5
MOLECULAR WEIGHT: 246.194 g/mol
BEILSTEIN REGISTRY No.: 90221
EC No: 200-072-5
MDL No: MFCD00006530
SKU 02105551-CF Categories , , Tag

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PRODUCT DESCRIPTION

5-Fluorodeoxyuridine Application Notes 5-Fluorodeoxyuridine can be used to target thymidylate synthetase in cancer chemotherapy. Experimental anticancer agent shown to have activity against a variety of malignant neoplasms, including mouse mammary tumors and colorectal carcinomas. Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. Key Applications Chemotherapy
SPECIFICATIONS
SKU: 02105551-CF
Base Catalog Number: 105551
Alternate Names: 2'-Deoxy-5-Fluorouridine; Floxuridine; 5-Fluoro-2'-deoxyuridine; FUDR; dFUR
Beilstein Registration No : 90221
Biochemical Physiological Actions : Antineoplastic drug that acts as a potent inhibitor of thymidylate synthetase. Resistance to FUdR can develop in cancer cell cultures, among other means, by low-level Mycoplasma infection.
CAS : # 50-91-9
EC No : 200-072-5
Extinction Coefficient : EmM = 8.91 (0.1 M phosphate buffer, pH 6.0) (Lit.)
Format : Powder
Hazard Statements : H301
MDL No : MFCD00006530
Melting Point : 302 to 304° F (NTP, 1992)
Molecular Formula : C9H11FN2O5
Molecular Weight : 246.194 g/mol
Optical Rotation: +37 ° (10 mg/mL in water at 25 °C) (Lit.)
pKa : 7.6 (Lit.)
PPE : Dust mask , Eyeshields, Faceshields, Gloves
Purity : >98%
RTECS No : YU7525000
Safety Symbol : GHS06
Solubility : Water Solubility11900 mg/L
UV Visible Absorbance : ?max (water) : 266 - 270 nm
Vapor Pressure : 7.6X10-13 mm Hg at 25 deg C (est)

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