(6R)-5,6,7,8-Tetrahydro-l-biopterin dihydrochloride

Key Features and Details

(6R)-5,6,7,8-Tetrahydro-L-Biopterin Dihydrochloride

SYNONYMS: (6R)-BH4-Amino-6-(1,2-dihydroxy-propyl)-5,6,7,8-tetrahydro-4(1H)-pteridinone dihydrochloride; BH4; (6R)-BH4; (6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride; Sapropterin; Dapropterin
CAS: # 17528-72-2
MOLECULAR WEIGHT: 241.251 g/mol
MDL No: MFCD00891665
SKU 02153622-CF Categories , , Tag

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(6R)-5,6,7,8-Tetrahydro-L-Biopterin Dihydrochloride Application Notes (6R)-5,6,7,8-Tetrahydro-L-biopterin Dihydrochloride is necessary in vivo for the conversion of phenylalanine to tyrosine and for the production of the hormone epinephrine and of the monoamine neurotransmitters, serotonin, dopamine, and norepinephrine. It is also involved in apoptosis and other cellular events mediated by nitric oxide production and catalyzes the cleavage of alkylglycerol ethers. (6R)-BH4 has been used as a buffer component for assaying tyrosine hydroxylase enzyme activity in mouse brain tissues. Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. Key Applications Cofactor
SKU: 02153622-CF
Base Catalog Number: 153622
Alternate Names: (6R)-BH4-Amino-6-(1,2-dihydroxy-propyl)-5,6,7,8-tetrahydro-4(1H)-pteridinone dihydrochloride; BH4; (6R)-BH4; (6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride; Sapropterin; Dapropterin
Biochemical Physiological Actions : Natural cofactor for phenylalanine hydroxylase, tyrosine hydroxylase, tryptophan hydroxylase, and nitric oxide synthetase.
CAS : # 17528-72-2
Extinction Coefficient : EM(216 nm)=15,400 (0.1 N HCl); (264 nm) = 13,750 (0.1 N HCl)(Lit.)
Format : Powder
Hazard Statements : H302
MDL No : MFCD00891665
Melting Point : 250 - 255 °C (hydrochloride salt)
Molecular Formula : C9H15N5O3·2HCl
Molecular Weight : 241.251 g/mol
Optical Rotation: [a]D = -6.6° to –7.6° (C = 1 in 0.1 N HCl)(Lit.)
RTECS No : UO3516000
Safety Symbol : GHS07

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