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Ampicillin
Key Features and Details
Ampicillin
SYNONYMS: D[-]-a-Aminobenzylpenicillin; 6-[D(-)-a-Aminophenylacetamido]penicillanic acid
CAS: #
69-53-4
MOLECULAR FORMULA: C16H19N3O4S
MOLECULAR WEIGHT: 349.405 g/mol
BEILSTEIN REGISTRY No.: 1090925
EC No: 200-709-7
MDL No: MFCD00005175
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PRODUCT DESCRIPTION
Ampicillin
Application Notes
Ampicillin is used to select bacteria cells with specific resistance during general microbiology studies. It is used to study antibiotic resistance and penetration limitations, the synergy between multiple antibiotics, certain bloodstream infections, and has been used to develop PCR assays to detect resistance genes in cerebrospinal fluid.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Antibacterial | Antibiotics
SPECIFICATIONS
SKU: 02190146-CF
Base Catalog Number: 190146
Alternate Names: D[-]-a-Aminobenzylpenicillin; 6-[D(-)-a-Aminophenylacetamido]penicillanic acid
Beilstein Registration No
: 1090925
Biochemical Physiological Actions
: Ampicillin is a ß-lactam antibiotic with an amino group attached to the penicillin structure. Inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: Cleavage of ß-lactam ring of ampicillin by ß-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
CAS
: #
69-53-4
EC No
: 200-709-7
Format
: White powder
Grade
: Anhydrous
Hazard Statements
: H315-H317-H319-H334-H335
MDL No
: MFCD00005175
Melting Point
: 388 to 392° F (decomposes) (NTP, 1992)
Molecular Formula
: C16H19N3O4S
Molecular Weight
: 349.405 g/mol
pKa
: pKa = 2.5 (-COOH) pKa = 7.3 (-NH2) at 25 °C
PPE
: Dust mask, Eyeshields, Faceshields, Gloves
RTECS No
: XH8350000
Safety Symbol
: GHS07, GHS08
Solubility
: 1 to 10 mg/mL at 70° F (NTP, 1992)
Typical Working Concentration
: 100 mg/liter for both gram positive and gram negative bacteria
