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Antipain hydrochloride
Key Features and Details
Antipain Hydrochloride
SYNONYMS: L-Valinamide; [(S)-1-Carboxy-2-phenylethyl]- carbamoyl-Arg-Val-Arg-al; [(S)-1-Carboxy-2-phenylethyl]carbamoyl-L-arginyl-L-valyl-argininal; [(S)-1-Carboxy-phenethyl]-carbamoyl-Arg-Val-Arg-aldehyde
CAS: #
37682-72-7
MOLECULAR FORMULA: C27H44N10O6 (free acid)
MOLECULAR WEIGHT: 677.629 g/mol
EC No: 253-631-0
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PRODUCT DESCRIPTION
Antipain Hydrochloride
Application Notes
Antipain inhibits trypsin, papain, and catherpsins A and B (a reversible inhibitor of cysteine and serine proteases). It is used to evaluate the role of proteases in cell transformations. It is used to help identify new proteases.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Reversible inhibitor of serine/cysteine proteases
SPECIFICATIONS
SKU: 02152843-CF
Base Catalog Number: 152843
Alternate Names: L-Valinamide; [(S)-1-Carboxy-2-phenylethyl]- carbamoyl-Arg-Val-Arg-al; [(S)-1-Carboxy-2-phenylethyl]carbamoyl-L-arginyl-L-valyl-argininal; [(S)-1-Carboxy-phenethyl]-carbamoyl-Arg-Val-Arg-aldehyde
Biochemical Physiological Actions
: Reversible inhibitor of serine/cysteine proteases and some trypsin-like serine proteases. Its action resembles leupeptin; however, its plasmin inhibition is less and its cathepsin A inhibition is more than that observed with leupeptin. Chronic administration can reduce the frequency of chemically induced transformation in BALB/c-/3T3 cells.
CAS
: #
37682-72-7
EC No
: 253-631-0
Format
: Powder
Hazard Statements
: H302
Molecular Formula
: C27H44N10O6 (free acid)
Molecular Weight
: 677.629 g/mol
PPE
: Eyeshields, Gloves, respirator filter
RTECS No
: YV9350700
Safety Symbol
: GHS07
Typical Working Concentration
: EIA: 10 µg/mL in PBS. We recommend that the individual lab obtain their own optimal dilution for their assay.
