Aprotinin, solution
Key Features and Details
Aprotinin In Solution
SYNONYMS: Antagosan; Anikrein; Antilysin(e); Basic pancreatic trypsin inhibitor; BPTI; Bayer A 128; Kallikrein-trypsin inactivator; Fosten; Iniprol; Kunitz protease inhibitor; Onquinin; Repulson; RP-9921; Ryker 52G; Trasylol; Triazinin; Zymofren;Trypsin inhibitor (basic)
CAS: #
9087-70-1
MOLECULAR FORMULA: C284H432N84O79S7
MOLECULAR WEIGHT: 6511.509 g/mol
EC No: 232-994-9
MDL No: MFCD00130541
SKU
02190779-CF
Categories Biochemicals, Life Sciences, Proteins and Derivatives, Tissue and Blood Products
Tag Mpbio
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PRODUCT DESCRIPTION
Aprotinin In Solution
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Trypsin Inhibitor
SPECIFICATIONS
SKU: 02190779-CF
Base Catalog Number: 190779
Alternate Names: Antagosan; Anikrein; Antilysin(e); Basic pancreatic trypsin inhibitor; BPTI; Bayer A 128; Kallikrein-trypsin inactivator; Fosten; Iniprol; Kunitz protease inhibitor; Onquinin; Repulson; RP-9921; Ryker 52G; Trasylol; Triazinin; Zymofren;Trypsin inhibitor (basic)
Biochemical Physiological Actions
: Aprotinin is a competitive serine protease inhibitor that forms stable complexes with and blocks the active sites of enzyme. This binding is reversible, and most aprotinin-protease complexes will dissociate at extreme pH levels >10 or <3. Structurally, Aprotinin is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges.
CAS
: #
9087-70-1
EC No
: 232-994-9
Extinction Coefficient
: 8.3 (water) (280 nm)
Format
: Aseptically filled solution in 0.9% NaCl and 0.9% benzyl alcohol .
Grade
: Analytical
Isoelectric Point
: 10.5 10
MDL No
: MFCD00130541
Melting Point
: >100 °C
Molecular Formula
: C284H432N84O79S7
Molecular Weight
: 6511.509 g/mol
Optical Rotation: ~ 9 mg/mlBenzyl Alcohol
pKa
: Eyeshields, Gloves, half-mask respirator , multi-purpose combination respirator cartridge
Potency
: 5.0 - 6.4
RTECS No
: YN5080000
Specific Activity
: Soluble in water (10 mg/mL - completely soluble) and in aqueous buffers of low ionic strengths.
Sterility
: Bovine Lung
Sterilization of Solutions
: >10,000 KIU/mL
Storage
: BIOCHEMICALS