Aprotinin

Key Features and Details

Aprotinin

SYNONYMS: Pancreatic Basic Trypsin Inhibitor polypeptide; Antagosan; Antikrein; Trasylol; Zymofren; Antagosan; Anikrein; Antilysin(e); BPTI; Bayer A 128; Kallikrein-trypsin inactivator; Fosten; Iniprol; Kunitz protease inhibitor; Onquinin; Repulson; RP-9921; Ryker 52G; Triazinin; Zymofren
CAS: # 9087-70-1
MOLECULAR FORMULA: C284H432N84O79S7
MOLECULAR WEIGHT: 6511.509 g/mol
EC No: 232-994-9
MDL No: MFCD00130541

You need to register an account with us
to be able to place an order, Click to Register.

PRODUCT DESCRIPTION

Aprotinin Application Notes Small amounts of aprotinin can be added to tubes of drawn blood to enable laboratory measurement of rapidly degraded proteins such as glucagon. Aprotinin can be labelled with fluorescein isothiocyanate. The conjugate retains its antiproteolytic and carbohydrate-binding properties and has been used as a fluorescent histochemical reagent for staining glycoconjugates (mucosubstances) that are rich in uronic or sialic acids. In cell biology aprotinin is used as an enzyme inhibitor to prevent protein degradation during lysis or homogenization of cells and tissues . Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. Key Applications Enzyme inhibitor
SPECIFICATIONS
SKU: 02190382-CF
Base Catalog Number: 190382
Alternate Names: Pancreatic Basic Trypsin Inhibitor polypeptide; Antagosan; Antikrein; Trasylol; Zymofren; Antagosan; Anikrein; Antilysin(e); BPTI; Bayer A 128; Kallikrein-trypsin inactivator; Fosten; Iniprol; Kunitz protease inhibitor; Onquinin; Repulson; RP-9921; Ryker 52G; Triazinin; Zymofren
Biochemical Physiological Actions : Aprotinin is a competitive serine protease inhibitor that forms stable complexes with and blocks the active sites of enzyme. This binding is reversible, and most aprotinin-protease complexes will dissociate at extreme pH levels >10 or <3. Structurally, Aprotinin is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges.
CAS : # 9087-70-1
EC No : 232-994-9
Extinction Coefficient : 8.3 (water)(280 nm)
Grade : Analytical
Isoelectric Point : 10.5 10 (Lit.)
MDL No : MFCD00130541
Melting Point : >100 °C
Molecular Formula : C284H432N84O79S7
Molecular Weight : 6511.509 g/mol
PPE : Eyeshields, Gloves, respirator filter
RTECS No : YN5080000
Source : Bovine Lung
Specific Activity : ~6000 KIU/mg
Typical Working Concentration : Equimolar with protease (1-2 ug/mL).
Unit Definition : KIU: One KIU (Kallikrein Inactivating Unit) is identical to the quantity of protease inhibitor that has the ability to inhibit 2 Kallikrein units by 50% under optimal conditions.
UV Visible Absorbance : 277 ± 5 nm ?max (water)

© All rights reserved byJuniperlifesciences.com 2021

All logos and Trademarks are names the property of their respective owners.

Shopping Cart
Scroll to Top

Enquire

Submit your details and receive all the download links in your email

Login to your account
Login to your account