Key Features and Details
SYNONYMS: Ro 10-6338; 3-(aminosulfonyl)-5-(butylamino)- 4-phenoxybenzoic acid; 3-(butylamino)-4-phenoxy- 5-sulfamoylbenzoic acid
CAS: # 28395-03-1
MOLECULAR FORMULA: C17H20N2O5S
MOLECULAR WEIGHT: 364.416 g/mol
EC No: 249-004-6
MDL No: MFCD00078949
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Bumetanide Application Notes Bumetanide has been used to probe the role of prostaglandin E2 in the regulation of chloride secretion across porcine endometrial epithelial cells. A study of the effects of bumetanide application and subsequent sodium potassium chloride cotransporter (NKCC1) inhibition in cultured liver cells has indicated increased a1-smooth muscle actin expression in 2-day-cultured hepatic stellate cells. An investigation of lactacidosis treatment of suspended G6 glial cells with bumetanide included at 0.1 mM has shown diminished cell swelling due to lactacidosis. Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Base Catalog Number: 154263
Alternate Names: Ro 10-6338; 3-(aminosulfonyl)-5-(butylamino)- 4-phenoxybenzoic acid; 3-(butylamino)-4-phenoxy- 5-sulfamoylbenzoic acid
Biochemical Physiological Actions : Inhibitor of Na+/K+/Cl- cotransporter.
CAS : # 28395-03-1
EC No : 249-004-6
Format : Powder
MDL No : MFCD00078949
Melting Point : 230-231
Molecular Formula : C17H20N2O5S
Molecular Weight : 364.416 g/mol
PPE : Eyeshields, Gloves, respirator filter
Purity : =99%
RTECS No : DG4910000
Solubility : >54.7 [ug/mL]