Caerulein, sulfated

Key Features and Details

Caerulein, Sulfated

SYNONYMS: pyroGlu-Gln-Asp-Tyr[SO3H]-Thr- Gly-Trp-Met-Asp-Phe-NH2; Caerulein Sulfated; Cerulein; Ceruletide; [Tyr(SO3H)4]Caerulein
CAS: # 17650-98-5
MOLECULAR FORMULA: C58H73N13O21S2
MOLECULAR WEIGHT: 1352.412 g/mol
BEILSTEIN REGISTRY No.: 5422487
MDL No: MFCD00076478
SKU 02152860-CF Categories , , Tag

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PRODUCT DESCRIPTION

Caerulein, Sulfated Application Notes Caerulein is used to study cell signaling mediated by NF-kappaB upregulation of proteins such as intercellular adhesion molecule-1(ICAM-1) and inflammation related molecules such as NADPH oxidase and Janus kinase signal transducer. It prevents gall bladder pain, renal colic, and the pain of intermittent claudication. Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. Key Applications Used to study cell signaling mediated by NF-kappaB upregulation of proteins such as intercellular adhesion molecule-1(ICAM-1) and inflammation related molecules such as NADPH oxidase and Janus kinase signal transducer
SPECIFICATIONS
SKU: 02152860-CF
Base Catalog Number: 152860
Alternate Names: pyroGlu-Gln-Asp-Tyr[SO3H]-Thr- Gly-Trp-Met-Asp-Phe-NH2; Caerulein Sulfated; Cerulein; Ceruletide; [Tyr(SO3H)4]Caerulein
Beilstein Registration No : 5422487
Biochemical Physiological Actions : It is seen as an antagonist of endogenous opioids.
CAS : # 17650-98-5
Format : Powder
MDL No : MFCD00076478
Molecular Formula : C58H73N13O21S2
Molecular Weight : 1352.412 g/mol
PPE : Eyeshields, Gloves, respirator filter
Preparation Method : The peptide is to be dissolved in distilled, oxygen free or preferable sterile oxygen free water first. The concentration should be high enough to allow addition of buffer after the products is dissolved completely. If necessary diluted acetic acid or ammonium hydroxide, app. 1%, can be added to help solubilize the peptide. In those rare cases where solubilization is still not achieved, the solution may be sonicated briefly (up to 10 min, temperature shouldn't rise over 30-40 °C). In order to avoid serious solubility problems, buffer or saline should be added after the peptide is fully in solution.
Solubility : 1.16e-02 g/L

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