Cefotaxime, sodium salt, phytopure™

Key Features and Details

Number: 64485-93-4

SYNONYMS: Cefotaxime sodium; (6R-(6-a,7-b(Z)))-3-((Acetyloxy) methyl)-7- (((2-amino-4-thiazolyl) (methoxyimio) acetyl) amino)-8- oxo-5-thia-1- azabicyclo (4,2,0) oct-2-ene-2-carboxylic acid, sodium salt
CAS: # 64485-93-4
MOLECULAR FORMULA: C 16 H 16 N 5 O 7 S 2 Na
MOLECULAR WEIGHT: 477.40
BEILSTEIN REGISTRY No.: 5711411
EC No: 264-915-9
MDL No: MFCD00079073
SKU 02154947-CF Categories , , Tag

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PRODUCT DESCRIPTION

A cephalosporin antibiotic effective against gram-positive and gram-negative bacteria. It interferes with cell wall formation by inhibiting cross-linkage between the linear peptidoglycan polymer chains that make up a major component of the cell walls. Useful in plant cell culture because it doesn't affect the plasmids of developed vascular plants. Application Notes Cefotaxime is used for infections of the respiratory tract, skin, bones, joints, urogenital system, meninges, and bloodstream. It generally has good coverage against most Gram-negative bacteria, with the notable exception of Pseudomonas. It is also effective against most Gram-positive cocci except for Enterococcus. It is active against penicillin-resistant strains of Streptococcus pneumoniae. It has modest activity against the anaerobic Bacteroides fragilis. In meningitis, cefotaxime crosses the blood–brain barrier better than cefuroxime. Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. Key Applications Cell wall inhibitor
SPECIFICATIONS
SKU: 02154947-CF
Base Catalog Number: 154947
Alternate Names: Cefotaxime sodium; (6R-(6-a,7-b(Z)))-3-((Acetyloxy) methyl)-7- (((2-amino-4-thiazolyl) (methoxyimio) acetyl) amino)-8- oxo-5-thia-1- azabicyclo (4,2,0) oct-2-ene-2-carboxylic acid, sodium salt
Beilstein Registration No : 5711411
Biochemical Physiological Actions : Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.
CAS : # 64485-93-4
EC No : 264-915-9
Hazard Statements : H317-H334
MDL No : MFCD00079073
Molecular Formula : C 16 H 16 N 5 O 7 S 2 Na
Molecular Weight : 477.40
PPE : Dust mask, Eyeshields, Faceshields, Gloves
Purity : =95%
RTECS No : XI0250000
Safety Symbol : GHS08
Solubility : 68.2 [ug/mL]

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