Choline chloride
Key Features and Details
Choline chloride is an organic compound and a quaternary ammonium salt. It is a weak acid. Choline chloride is the salt of the naturally occurring choline, the pre-stage of the neurotransmitter acetylcholine, which is important for mnemonic and thought-processes. Choline occurs naturally in fungi, hop and kingcups and as integral part of lecithin. Choline chloride is a common food additive in animal husbandry
SYNONYMS: Choline Hydrochloride; Hepacholine; (2-Hydroxyethyl)Trimethyl-Ammonium Chloride
CAS: #
67-48-1
MOLECULAR FORMULA: C5H14NOCl
MOLECULAR WEIGHT: 139.63
BEILSTEIN REGISTRY No.: 3563126
EC No: 200-655-4
MDL No: MFCD00011721
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PRODUCT DESCRIPTION
Choline chloride is an organic compound and a quaternary ammonium salt. It is a weak acid. Choline chloride is the salt of the naturally occurring choline, the pre-stage of the neurotransmitter acetylcholine, which is important for mnemonic and thought-processes. Choline occurs naturally in fungi, hop and kingcups and as integral part of lecithin. Choline chloride is a common food additive in animal husbandry
Application Notes
Choline chloride is used as a source of methyl groups for methyl-transfer reactions.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Choline acetyltransferase substrate
SPECIFICATIONS
SKU: 02194639-CF
Base Catalog Number: 194639
Alternate Names: Choline Hydrochloride; Hepacholine; (2-Hydroxyethyl)Trimethyl-Ammonium Chloride
Beilstein Registration No
: 3563126
Biochemical Physiological Actions
: The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes.
CAS
: #
67-48-1
Density
: 1.1 g/cm3 at 20 °C (Lit.)
EC No
: 200-655-4
Format
: White Crystalline Powder, Hard
Grade
: Cell Culture
Hazard Statements
: H315-H319-H335
MDL No
: MFCD00011721
Melting Point
: 302-305 °C (dec.)(lit.)
Molecular Formula
: C5H14NOCl
Molecular Weight
: 139.63
Partition Coefficient
: n octanol/water (logKow): -3.77 at 25 °C (lit.)
pH
: Neutral to Litmus
PPE
: Dust mask, Eyeshields, Gloves
Purity
: >99%
RTECS No
: KH2975000
Safety Symbol
: GHS08
Solubility
: Soluble in water: (10% aq soln) Clear, Colorless Solution.
Vapor Pressure
: 10 hPa at 20 °C (Lit.)
