Collagenase, cell preparation grade, =160 U/mg

Collagenase Application Notes Crude Collagenases are suitable for isolation of cells from many types of animal tissue. Collagenase has found widespread application in the isolation of specific cell types from attendant connective tissue. For example, there is much interest in the experimental transplantation of pancreatic islet cells to alleviate diabetic symptoms. Intact parenchymal cells from rat liver tissue have also been isolated. The wide spectrum of activity of crude collagenase makes it especially useful as a debriding agent. It has been indicated its possible value for the treatment of herniated discs. For collagen structural and biosynthetic studies researchers generally use more highly purified collagenase preparations free of other proteolytic activities. For tissue dissociation most researchers employ either crude collagenase preparations or chromatographically purified collagenase combined with other enzymes such as elastase, trypsin, and/or papain. Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.