Compound 48/80
Key Features and Details
Compound 48/80
CAS: #
94724-12-6
MOLECULAR WEIGHT: 519.73 g/mol
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PRODUCT DESCRIPTION
Compound 48/80
Application Notes
Compound 48/80 used to induce degranulation of GnRH-like immunoreactivity of mast cells in the brain and mesentery and for elucidating the mechanism by which anti-allergic medications suppress conjunctivitis.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Potent histamine releasing agent
SPECIFICATIONS
SKU: 02159026-CF
Base Catalog Number: 159026
Biochemical Physiological Actions
: Potent histamine releasing agent, primarily from mast cells, with a subsequent depletion of tissue histamine. It is the action of mast cell mediators on the cardiovascular system that leads to circulatory collapse. The toxicity is due to more than histamine release. It is a potent inhibitor of phospholipase C. Activates G proteins by a mechanism analogous to that of mastorparan. Inhibits calmodulin and human platelet PLC and exhibits a concentration dependent biphasic modulation of human platelet PLA2.
CAS
: #
94724-12-6
Format
: Powder
Hazard Statements
: H301-H311-H331
Molecular Weight
: 519.73 g/mol
PPE
: Eyeshields, Faceshields, Gloves, respirator cartridges
RTECS No
: Gk2402500
Safety Symbol
: GHS06
