Dacarbazine , 250 mg
Key Features and Details
SYNONYMS: 5-[3,3-Dimethyl-1-triazenyl]imidazole-4-carboxamide; DTIC
CAS: # 4342-03-4
MOLECULAR FORMULA: C 6 H 10 N 6 O
MOLECULAR WEIGHT: 182.2
EC No: 224-396-1
MDL No: MFCD00057167
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Base Catalog Number: 15751983
Alternate Names: 5-[3,3-Dimethyl-1-triazenyl]imidazole-4-carboxamide; DTIC
Biochemical Physiological Actions : Dacarbazine has significant activity against melanomas. It is a synthetic analog of naturally occurring purine precursor 5-amino-1H-imidazole-4-carboxamide (AIC). Dacarbazine appears to exert cytotoxic effects by acting as an alkylating agent, by inhibiting DNA synthesis as a purine analog, and by inducing apoptosis. Dacarbazine is not cell cycle-phase specific.
CAS : # 4342-03-4
EC No : 224-396-1
Hazard Statements : H312-H315-H319-H332-H335-H350
MDL No : MFCD00057167
Melting Point : 202 °C (Lit.)
Molecular Formula : C 6 H 10 N 6 O
Molecular Weight : 182.2
PPE : Eyeshields, full-face particle respirator, Gloves, respirator filter, respirator cartridges
RTECS No : NI3950000
Safety Symbol : GHS07, GHS08
Solubility : Soluble in 1 M HCl (40 mg/mL - clear to turbid, faint yellow solution).