Dacarbazine , 250 mg
Key Features and Details
SYNONYMS: 5-[3,3-Dimethyl-1-triazenyl]imidazole-4-carboxamide; DTIC
CAS: # 4342-03-4
MOLECULAR FORMULA: C
6
H
10
N
6
O
MOLECULAR WEIGHT: 182.2
EC No: 224-396-1
MDL No: MFCD00057167
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PRODUCT DESCRIPTION
SPECIFICATIONS
SKU: 0215751983
Base Catalog Number: 15751983
Alternate Names: 5-[3,3-Dimethyl-1-triazenyl]imidazole-4-carboxamide; DTIC
Biochemical Physiological Actions
: Dacarbazine has significant activity against melanomas. It is a synthetic analog of naturally occurring purine precursor 5-amino-1H-imidazole-4-carboxamide (AIC). Dacarbazine appears to exert cytotoxic effects by acting as an alkylating agent, by inhibiting DNA synthesis as a purine analog, and by inducing apoptosis. Dacarbazine is not cell cycle-phase specific.
CAS
: # 4342-03-4
EC No
: 224-396-1
Hazard Statements
: H312-H315-H319-H332-H335-H350
MDL No
: MFCD00057167
Melting Point
: 202 °C (Lit.)
Molecular Formula
: C
6
H
10
N
6
O
Molecular Weight
: 182.2
PPE
: Eyeshields, full-face particle respirator, Gloves, respirator filter, respirator cartridges
RTECS No
: NI3950000
Safety Symbol
: GHS07, GHS08
Solubility
: Soluble in 1 M HCl (40 mg/mL - clear to turbid, faint yellow solution).
