Daunomycin hydrochloride
Key Features and Details
Daunomycin Hydrochloride
SYNONYMS: Daunorubicin hydrochloride; Daunorubicine hydrochloride; Leukaemomycin C; (8S-cis)-8-Acetyl-10- [(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxyl]-7,8,9,10-tetrahydro- 6,8,11- trihydroxy-1- methoxy-5,12-naphthacenedione hydrochloride
CAS: #
23541-50-6
MOLECULAR FORMULA: C27H29NO10·HCl
MOLECULAR WEIGHT: 563.984 g/mol
BEILSTEIN REGISTRY No.: 4229221
EC No: 245-723-4
MDL No: MFCD04974507
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PRODUCT DESCRIPTION
Daunomycin Hydrochloride
Application Notes
Daunorubicin hydrochloride is used in photostability , antileukemic, and drug metabolism studies.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Photostability | Antileukemic | Drug metabolism studies
SPECIFICATIONS
SKU: 02150777-CF
Base Catalog Number: 150777
Alternate Names: Daunorubicin hydrochloride; Daunorubicine hydrochloride; Leukaemomycin C; (8S-cis)-8-Acetyl-10- [(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxyl]-7,8,9,10-tetrahydro- 6,8,11- trihydroxy-1- methoxy-5,12-naphthacenedione hydrochloride
Beilstein Registration No
: 4229221
Biochemical Physiological Actions
: Daunorubicin inhibits DNA and RNA synthesis as sequence specific ds-DNA intercalating agent. On binding to DNA, daunomycin intercalates, with its daunosamine residue directed toward the minor groove. Daunomycin effectively binds to every 3 base pairs which causes unwinding.
CAS
: #
23541-50-6
EC No
: 245-723-4
Format
: Powder
Hazard Statements
: H301-H334-H351
MDL No
: MFCD04974507
Melting Point
: 370 to 374° F (decomposes) (NTP, 1992)
Molecular Formula
: C27H29NO10·HCl
Molecular Weight
: 563.984 g/mol
PPE
: Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator cartridge respirator filter
RTECS No
: HB7878000
Safety Symbol
: GHS06, GHS08
Solubility
: Soluble (NTP, 1992)
Source
: Streptomyces peucetius
