Dexamethasone 21-acetate, 500 mg

Key Features and Details

SYNONYMS: 9a-Fluoro-16a-methyl-11ß,17a,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate; 9a-Fluoro-16a-methylprednisolone-21-acetate; Prednisolone F acetate
CAS: # 1177-87-3
MOLECULAR FORMULA: C24H31FO6
MOLECULAR WEIGHT: 434.5
BEILSTEIN REGISTRY No.: 2342608
EC No: 214-646-8
MDL No: MFCD00027407
SKU 0219004190 Categories , , Tag

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PRODUCT DESCRIPTION

Dexamethasone 21-acetate is an anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S transition in osteoblasts and inhibition of phosphorylation of Rb protein. Dexamethasone has been observed to induce apoptosis in human thymocytes and eosinophils but to inhibit apoptosis in neutrophils. Application Notes Dexamethasone 21-acetate is a glucocorticoid anti-inflammatory agent. Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. Key Applications Anti-inflammatory
SPECIFICATIONS
SKU: 0219004190
Base Catalog Number: 190041
Alternate Names: 9a-Fluoro-16a-methyl-11ß,17a,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate; 9a-Fluoro-16a-methylprednisolone-21-acetate; Prednisolone F acetate
Beilstein Registration No : 2342608
Biochemical Physiological Actions : An anti-inflammatory glucocorticoid.
CAS : # 1177-87-3
EC No : 214-646-8
Hazard Statements : H317
MDL No : MFCD00027407
Melting Point : 232 - 233.5 °C(lit.)
Molecular Formula : C24H31FO6
Molecular Weight : 434.5
RTECS No : TU4050000
Safety Symbol : GHS07
Solubility : Soluble in acetone (100mg/mL - Clear, Colorless to Light Yellow Solution).

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