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Doxycycline hydrochloride
Key Features and Details
Doxycycline Hydrochloride
SYNONYMS: Biocamycin; Doxigalumicina; Doxycycline hyclate; Doxy-II; Midoxin; Novadox; Retens; Tetradox; Vibradox; Hydramycin; 2-Naphthacenecarboxamide, 4-(dimethylamino)- 1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride
CAS: #
10592-13-9
MOLECULAR FORMULA: C22H24N2O8 HCl
MOLECULAR WEIGHT: 480.898 g/mol
BEILSTEIN REGISTRY No.: 5702728
EC No: 234-198-7
MDL No: MFCD07357237
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PRODUCT DESCRIPTION
Doxycycline Hydrochloride
Application Notes
Doxycycline hyclate is a synthetic oxytetracycline derivative. It has been used to eliminate Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs and to eliminate Ixodes scapularis ticks. It is used to inhibit matrix metalloproteinases and has been used to inhibit the inflammatory response of Lyme Disease.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Antibiotic
SPECIFICATIONS
SKU: 02195044-CF
Base Catalog Number: 195044
Alternate Names: Biocamycin; Doxigalumicina; Doxycycline hyclate; Doxy-II; Midoxin; Novadox; Retens; Tetradox; Vibradox; Hydramycin; 2-Naphthacenecarboxamide, 4-(dimethylamino)- 1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride
Beilstein Registration No
: 5702728
Biochemical Physiological Actions
: Derivative of oxytetracycline. A broad spectrum inhibitor used to inhibit matrix metallo-proteinases (MMP) such as type 1 collagenase in studies on wound healing and tissue remodeling.Doxycycline is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. It is a Broad spectrum antibiotic and bacteriostatic. Doxycycline shows antiprotozoal properties and is a potent inhibitor of MMPs (matrix metalloproteinases) in vivo. Doxycycline is frequently used to treat Lyme disease, chronic prostatitis, sinusitis, pelvic inflammatory disease acne, rosacea, and rickettsial infections and prophylaxis of anthrax (caused by Bacillus anthracis). It is also effective against Yersinia pestis. Treatment with doxycycline inhibits collagen synthesis.
CAS
: #
10592-13-9
EC No
: 234-198-7
Hazard Statements
: H302-H315-H319-H335
MDL No
: MFCD07357237
Molecular Formula
: C22H24N2O8 HCl
Molecular Weight
: 480.898 g/mol
pKa
: (10 mg/ml)
Potency
: 43134
PPE
: dust mask , Eyeshields, Gloves
Preparation Method
: P261-P305 + P351 + P338
RTECS No
: QI8925000
Source
: Soluble in water (10 mg/mL - clear; yellowish to yellowish-green solution) and DMSO: soluble (50 mg/mL).
Storage
: BIOCHEMICALS
Unit Definition
: It is typically used at a concentration of 20 ug/mL and is stable in media at 37 °C for approximately 5 days.
