Ebselen, 20 mg

Key Features and Details

SYNONYMS: 2-Phenyl-1,2-benzisoselenazol-3(2H)-one
CAS: # 60940-34-3
MOLECULAR FORMULA: C13N9NOSe
MOLECULAR WEIGHT: 274.2
MDL No: MFCD00210937
SKU 0215880920 Categories , , Tag

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PRODUCT DESCRIPTION

Ebselen is a novel selenium-containing anti-flammatory agent. Application Notes Ebselen inhibits 5-LO, CO, NADPH oxidase, and protein kinase C. It is a potent antioxidant. It possesses a unique glutathione peroxidase-like activity. It is also shown to be an inhibitor of free radical induced apoptosis and neuroprotective agent. Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. Key Applications Potent antioxidant
SPECIFICATIONS
SKU: 0215880920
Base Catalog Number: 15880920
Alternate Names: 2-Phenyl-1,2-benzisoselenazol-3(2H)-one
Biochemical Physiological Actions : Ebselen inhibits mammalian lipoxygenases in the absence of thiol groups, and glutathione S-transferase and papain via the interaction with cysteine residues. Also inhibits indoleamine 2,3-dioxygenase by covalently modifying a cysteine residue, the effect being reversible with dithiothreitol. Inhibits oxidation of low density lipoproteins (LDL).
CAS : # 60940-34-3
Hazard Statements : H301-H331-H373-H410
MDL No : MFCD00210937
Melting Point : 180 - 181 °C (Lit.)
Molecular Formula : C13N9NOSe
Molecular Weight : 274.2
RTECS No : DE4140750
Safety Symbol : GHS06, GHS08, GHS09
Solubility : Soluble in DMSO (25 mg/mL) and ethanol (10 mg/mL). Also soluble in chloroform (19.60 - 20.40 mg/mL - clear yellow solution).

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