Ethylene glycol-bis-(?-amino-ethylether)-N,N,N',N'-tetraacetic acid
Key Features and Details
Ethylene Glycol-Bis-(?-Amino-Ethylether)-N,N,N’,N’-Tetraacetic Acid
SYNONYMS: EGTA; GEDTA; O,O'-bis(2-aminoethyl)ethyleneglycol-N,N,N',N'-tetraacetic acid; Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetracetic acid; Egtazic acid; Ethylene-bis(oxyethylenenitrilo)tetraacetic acid; Glycol ether diamine tetraacetic acid
CAS: #
67-42-5
MOLECULAR FORMULA: C14H24N2O10
MOLECULAR WEIGHT: 380.35 g/mol
BEILSTEIN REGISTRY No.: 1717370
EC No: 200-651-2
MDL No: MFCD00004291
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PRODUCT DESCRIPTION
Ethylene Glycol-Bis-(?-Amino-Ethylether)-N,N,N',N'-Tetraacetic Acid
Application Notes
Ethylene Glycol-bis-(beta-aminoethylether)-N,N,N',N'-tetraacetic Acid is a chelating agent for determination of calcium in the presence of magnesium; it can also detect cadmium in the presence of zinc. It is also useful for the removal of heavy metal ions in biological systems. It is shown to activate Ca2+- stimulated ATPase in rat liver plasma membranes and induce apoptosis in PC12 cells. It also inhibits the zinc-dependent endopeptidases, matrix metalloproteinases.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Chelating agent
SPECIFICATIONS
SKU: 02194823-CF
Base Catalog Number: 194823
Alternate Names: EGTA; GEDTA; O,O'-bis(2-aminoethyl)ethyleneglycol-N,N,N',N'-tetraacetic acid; Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetracetic acid; Egtazic acid; Ethylene-bis(oxyethylenenitrilo)tetraacetic acid; Glycol ether diamine tetraacetic acid
Beilstein Registration No
: 1717370
CAS
: #
67-42-5
EC No
: 200-651-2
Format
: Powder
Grade
: Molecular Biology
MDL No
: MFCD00004291
Molecular Formula
: C14H24N2O10
Molecular Weight
: 380.35 g/mol
pKa
: < 2, 2.7, 8.8, and 9.5 (Lit.)
PPE
: Eyeshields, Gloves, Respirator filter
Purity
: =97%
RTECS No
: AH3760000
Typical Working Concentration
: as a metalloprotease inhibitor (effective concentration is typically 1 to 10 µM)
