Forskolin
Key Features and Details
Forskolin
SYNONYMS: 7ß-Acetoxy-8,13-epoxy-1a,6ß,9a-trihydroxylabd-14-en-11-one; Coleonol; Colforsin
CAS: #
66575-29-9
MOLECULAR FORMULA: C22H34O7
MOLECULAR WEIGHT: 410.507 g/mol
BEILSTEIN REGISTRY No.: 1692716
EC No: 266-410-9
MDL No: MFCD00082317
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PRODUCT DESCRIPTION
Forskolin
Application Notes
Forkolin is reported to demonstrate positive inotropic and heart rate-increasing activity at low doses in animals. Also functions as an antihypertensive and vasodilator at higher doses. Activates adenylcyclase in rat liver membranes.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Antihypertensive | Vasodilator
SPECIFICATIONS
SKU: 02190669-CF
Base Catalog Number: 190669
Alternate Names: 7ß-Acetoxy-8,13-epoxy-1a,6ß,9a-trihydroxylabd-14-en-11-one; Coleonol; Colforsin
Beilstein Registration No
: 1692716
Biochemical Physiological Actions
: Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration. Forskolin effects calcium currents and inhibits MAP kinase.
CAS
: #
66575-29-9
EC No
: 266-410-9
Hazard Statements
: H312
MDL No
: MFCD00082317
Molecular Formula
: C22H34O7
Molecular Weight
: 410.507 g/mol
PPE
: Dust mask type , Eyeshields, Gloves
RTECS No
: QL6150000
Safety Symbol
: GHS07
Source
: Coleus forskohlii
