Gentamicin sulfate, USP Grade
Key Features and Details
Inhibits the growth of a wide variety of Gram-positive and Gram-negative microorganisms
For use in cell culture applications at 5 ml/L
Used as a selection agent (gentamicin-resistance gene) in molecular biology applications
SYNONYMS: Garamycin; Gentamicin sulfate salt; Gentiomycin C
CAS: #
1405-41-0
MOLECULAR WEIGHT: 1488.8 g/mol
EC No: 215-778-9
MDL No: MFCD00270181
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PRODUCT DESCRIPTION
Gentamicin Sulfate
Application Notes
Gentamicin sulpahte is used as a selection agent (gentamicin-resistance gene) in molecular biology applications.It is used to treat many types of bacterial infections, particularly those caused by Gram-negative organisms.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Aminoglycosides | Antibacterial
SPECIFICATIONS
SKU: 02190057-CF
Base Catalog Number: 190057
Alternate Names: Garamycin; Gentamicin sulfate salt; Gentiomycin C
Biochemical Physiological Actions
: Gentamicin causes codon misreading by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site. The bactericidal effect of gentamicin on Pseudomonas aeruginosa is exerted by the binding of gentamicin to the outer membrane, where it displaces natural cations, destabilizes the membrane, and forms holes in the cell surface. Antimicrobial spectrum: Gram-negative bacteria, Staphylococcus aureus and other Gram-positive bacteria.
CAS
: #
1405-41-0
EC No
: 215-778-9
Grade
: USP
Hazard Statements
: H317-H334
MDL No
: MFCD00270181
Molecular Weight
: 1488.8 g/mol
Optical Rotation: =1.0%
pKa
: 3.5 - 5.5(1 in 25, in water)
Preparation Method
: P261-P280-P342 + P311
RTECS No
: LY2625000
Safety Symbol
: =1.0%
Source
: H2O: soluble 50 mg/mL
Storage
: BIOCHEMICALS
Unit Definition
: This product is recommended for use at 50 mg/L.
