Guanosine-5'-triphosphate disodium salt,=95%
Key Features and Details
Substrate for RNA polymerases and GTPases including G-protein coupled receptor (GPCR) GTPases and cell signaling and cycling associated guanine nucleotide exhange factors (GEF)
SYNONYMS: GTP disodium salt; 5'-GTP-Na2
CAS: #
36051-31-7
MOLECULAR FORMULA: C10H14N5O14P3Na2
MOLECULAR WEIGHT: 589.126 g/mol
EC No: 259-940-7
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PRODUCT DESCRIPTION
Guanosine-5'-Triphosphate Disodium Salt
Application Notes
Guanosine 5'-triphosphate (GTP), a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR) GTPases and cell signaling and cycling associated guanine nucleotide exhange factors (GEF).
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Substrate for RNA polymerases
SPECIFICATIONS
SKU: 02195213-CF
Base Catalog Number: 195213
Alternate Names: GTP disodium salt; 5'-GTP-Na2
Biochemical Physiological Actions
: GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.
CAS
: #
36051-31-7
EC No
: 259-940-7
Format
: Powder
Molecular Formula
: C10H14N5O14P3Na2
Molecular Weight
: 589.126 g/mol
Optical Rotation: [a]20/D -24±2°, c = 1% in 0.5 M Na2HPO4
PPE
: Eyeshields, Faceshields, Gloves, Respirator filter
Purity
: =95%
UV Visible Absorbance
: ? max (water): 252 ± 3 nm
