Hemin chloride from porcine

Key Features and Details

Hemin Chloride

SYNONYMS: Hemin Chloride; Chloroferriprotoporphyrin; Chlorohemin; Chloro(protoprophyrinato) iron (III); Ferriprotoporphyrin IX chloride; Hematin hydrochloride; Protohemin IX; (SP-5-13)-Chloro [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)- N21, N22, N23, N24] ferrate(2-) dihydrogen; Chloro [dihydrogen 3,7,12,17-tetramethyl-8,13-divinyl-2, 18-porphinedipropionato (2-)]iron; 1,3,5,8-tetramethyl-2,4-divinylporphine-6,7- dipropionic acid ferrichloride; Teichmann's crystals; Ferriheme chloride
CAS: # 16009-13-5
MOLECULAR FORMULA: C34H32ClFeN4O4
BEILSTEIN REGISTRY No.: 5229914
EC No: 240-140-1
MDL No: MFCD00010726
SKU 02198820-CF Categories , , , Tag

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PRODUCT DESCRIPTION

Hemin Chloride Application Notes Hemin is used in the management of porphyria attacks, particularly in acute intermittent porphyria.It may be used to study the expression and repression of heme oxygenase 1 (HO-1) as well as the activity of HO-1.Hemin is used for the following applications:• To study bacterial strains and growth conditions• Used in short-term colony assays (the culture medium consists of hemin along with other components)• Cell transfections• It may be used in ß-hematin formation assay for analyzing the inhibitory activity of MMV (Medicines for Malaria Venture) Malaria Box compounds against the formation of ß-hematin. Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
SPECIFICATIONS
SKU: 02198820-CF
Base Catalog Number: 198820
Alternate Names: Hemin Chloride; Chloroferriprotoporphyrin; Chlorohemin; Chloro(protoprophyrinato) iron (III); Ferriprotoporphyrin IX chloride; Hematin hydrochloride; Protohemin IX; (SP-5-13)-Chloro [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)- N21, N22, N23, N24] ferrate(2-) dihydrogen; Chloro [dihydrogen 3,7,12,17-tetramethyl-8,13-divinyl-2, 18-porphinedipropionato (2-)]iron; 1,3,5,8-tetramethyl-2,4-divinylporphine-6,7- dipropionic acid ferrichloride; Teichmann's crystals; Ferriheme chloride
Beilstein Registration No : 5229914
Biochemical Physiological Actions : Hemin, the oxidized version of heme, is an iron-containing prosthetic group for a diverse group of proteins. Free heme, which can be released from hemoglobin following hemolysis, is pro-inflammatory and contributes to iron-derived reactive oxygen species. Free hemin levels may be upregulated in various pathological conditions and can contribute to various inflammatory conditions including vascular disorders, renal failure, and immune-mediated disorders. Hemin may be used to study the expression and represson of heme oxygenase 1 (HO-1) as well as the activity of HO-1. Hematin is the "X factor" required to grown Haemophilus influenzae.
CAS : # 16009-13-5
EC No : 240-140-1
Format : Powder
MDL No : MFCD00010726
Molecular Formula : C34H32ClFeN4O4
PPE : Eyeshields, Gloves,respirator filter
Preparation Method : Typically prepared by heating a hemoglobin solution with acetic acid and sodium chloride.
Source : Porcine

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