Key Features and Details


SYNONYMS: IAN; alpha-Iodoacetamide; Monoiodoacetamide; 2-Iodoacetamide; Surauto
CAS: # 144-48-9
MOLECULAR WEIGHT: 184.964 g/mol
EC No: 205-630-1
MDL No: MFCD00008028
SKU 02100351-CF Categories , , Tag

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Iodoacetamide Application Notes Iodoacetamide is useful in peptide sequencing and as an irreversible enzyme inhibitor. Some enzymes iodoacetamide will inhibit include (but is not limited to): Alcohol dehydrogenase, Alkaline phosphatase (calf intestinal), beta-Amylase, Cathepsin B, Galactose oxidase, Heme oxygenase, L-Lysine decarboxylase. It will irreversibly inhibit the dephosphorylation of both epidermal growth factor receptor and platelet-derived growth factor receptor by alkylation at the active center of one or several protein tyrosine phosphatases in cell lines. Iodoacetamide will also irreversibly inhibit many cysteine proteases. Alkylating reagent for cysteine residues in peptide sequencing. By virtue of reaction with cysteine, it is an irreversible inhibitor of enzymes with cysteine at the active site. It reacts much more slowly with histidine residues, but that activity is responsible for inhibition of ribonuclease. Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. Key Applications Enzymes | Inhibitors | Substrates
SKU: 02100351-CF
Base Catalog Number: 100351
Alternate Names: IAN; alpha-Iodoacetamide; Monoiodoacetamide; 2-Iodoacetamide; Surauto
Beilstein Registration No : 1739080
CAS : # 144-48-9
EC No : 205-630-1
Format : Powder
Hazard Statements : H301-H317-H334-H413
MDL No : MFCD00008028
Molecular Formula : C2H4INO
Molecular Weight : 184.964 g/mol
PPE : Eyeshields, Faceshields, Gloves, Respirator cartridges
RTECS No : AC4200000
Safety Symbol : GHS06, GHS08
Typical Working Concentration : Cell culture substratum at 1-5 µg/cm2 or 0.5-50 µg/mL
UV Visible Absorbance : 267 ± 2 nm (water)
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