No products in the cart.
Ionomycin, 1 mg
Key Features and Details
Ionomycin
CAS: #
56092-81-0
MOLECULAR WEIGHT: 709.018 g/mol
BEILSTEIN REGISTRY No.: 3642126
MDL No: MFCD06798385
You need to register an account with us
to be able to place an order, Click to Register.
PRODUCT DESCRIPTION
Ionomycin
Application Notes
Ionomycin is a useful tool for increasing intracellular Ca2+ concentration . It is also used to equilibrate intracellular and extracellular calcium ion levels for in situ calibrations of fluorescent indicators. It is used to study the effects of calcium flux on endoplasmic reticulum (ER) stress, mitochodrial stress and intrinsic apoptosis mechanisms. It is also used to stimulate the intracellular production of the cytokines, interferon, perforin, IL-2, and IL-4 usually in conjunction with PMA.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Studies of Ca2+ transport | Equilibrate intracellular and extracellular calcium ion levels | Selective calcium ionophore
SPECIFICATIONS
SKU: 0215961101
Base Catalog Number: 15961101
Beilstein Registration No
: 3642126
Biochemical Physiological Actions
: Ionomycin is a Ca2+ ionophore that is more effective than A23187 as a mobile ion carrier for Ca2+. It induces apoptotic degeneration of embryonic cortical neurons, induces central demyelination and inhibits adrenal bovine TREK-1 channels.
CAS
: #
56092-81-0
Format
: Gel
Hazard Statements
: H302
MDL No
: MFCD06798385
Molecular Weight
: 709.018 g/mol
PPE
: Dust mask, Eyeshields, Gloves
Purity
: =90%
RTECS No
: NO0600000
Safety Symbol
: GHS07
Source
: Streptomyces conglobatus
Typical Working Concentration
: Ionomycin is used at concentration of 3nM and 2-4µM (whole cells).
