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Miconazole
Key Features and Details
Miconazole
SYNONYMS: 1-[2,4-Dichloro-ß-([2,4-dichlorobenzyl]oxy)phenethyl]imidazole; 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole; Monistat; Daktarin IV; Miconazolo; Miconazolum; Dactarin; Miconazol; Minostate; Brentan; Florid(nitrate)
CAS: #
22916-47-8
MOLECULAR FORMULA: C18H14Cl4N2O
MOLECULAR WEIGHT: 416.123 g/mol
EC No: 245-324-5
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PRODUCT DESCRIPTION
Miconazole
Application Notes
Miconazole is an imidazole antifungal agent that is used topically and by intravenous infusion. It is used to inhibit cytochrome P450 and to study automated luminescence-based cytochrome P450 profiling
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Anti-fungal agent
SPECIFICATIONS
SKU: 02193915-CF
Base Catalog Number: 193915
Alternate Names: 1-[2,4-Dichloro-ß-([2,4-dichlorobenzyl]oxy)phenethyl]imidazole; 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole; Monistat; Daktarin IV; Miconazolo; Miconazolum; Dactarin; Miconazol; Minostate; Brentan; Florid(nitrate)
Biochemical Physiological Actions
: Miconazole interacts with 14-a demethylase, a cytochrome P-450 enzyme necessary for ergosterol biosynthesis. The inhibition of ergosterol results in increased cellular permeability causing leakage of cellular contents. Miconazole may also inhibit endogenous respiration, interact with phospholipids in the cell membrane, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and interfere with triglyceride and phospholipid biosynthesis.
CAS
: #
22916-47-8
EC No
: 245-324-5
Format
: Powder
Melting Point
: 159-163 °C
Molecular Formula
: C18H14Cl4N2O
Molecular Weight
: 416.123 g/mol
RTECS No
: NI4770000
Solubility
: Water Solubility1g/100mL (20 °C)
