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Pancreatin, USP
Key Features and Details
Amylase Activity = 25 USP u/mg
Protease Activity = 25 USP u/mg
Lipase Activity = 2.0 USP u/mg
SYNONYMS: Diastase vera; Pancreatin from hog pancreas
CAS: #
8049-47-6
EC No: 232-468-9
MDL No: = 5%
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PRODUCT DESCRIPTION
Pancreatin, U.S.P.
Application Notes
Pancreatin from porcine pancreas has been used: for a study to assess the treatment of steatorrhea by lipase supplementation therapy for a study to investigate treatment options for pancreatic diabetes in patients experiencing the decompensated stage of chronic pancreatitis to safely and effectively remove formalin-fixed tissues from arterial grafts without causing structural damage and loss in fiber integrity to assess cleavage by digestive enzymes. for in vitro digestibility analysis and to test the sensitivities of cellulolytic bacteria inhibitors. along with amyloglucosidase for the in vitro digestion of starch in food samples.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Metabolism
SPECIFICATIONS
SKU: 02102557-CF
Base Catalog Number: 102557
Alternate Names: Diastase vera; Pancreatin from hog pancreas
Biochemical Physiological Actions
: Pancreatin contains enzymatic components including trypsin, amylase and lipase, ribonuclease, and protease, produced by the exocrine cells of the porcine pancreas. This combination of enzymes allows it to hydrolyze proteins, starch and fats. Pancreatin will convert not less than 25 times its weight of potato starch into soluble carbohydrates in 5 minutes in water at 40°C, will digest not less than 25 times its weight of casein in 60 minutes at pH 7.5 at 40°C and will release not less than microequivalents of acid per min per mg pancreatin from olive oil at pH 9.0 at 37°C.
CAS
: #
8049-47-6
EC No
: 232-468-9
Format
: Absent
Gel Strength
: Stable Powder; proteolytic and diastatic activities are 1X N.F. Std.
Grade
: USP
MDL No
: = 5%
Optical Rotation: Fat * if each activity is > 3× the minimum -=6.0% * if each activity is < 3× the minimum - = 3.0%
Preparation Method
: P261-P305 + P351 + P338-P342 + P311
RTECS No
: RT9033000
Source
: Partly soluble in water; insoluble in alcohol.
Specific Activity
: Porcine Pancreas
Sterility
: Amylase Activity = 25 USP u/mg Protease Activity = 25 USP u/mg Lipase Activity = 2.0 USP u/mg
Storage
: BIOCHEMICALS
