Paromomycin sulfate

Key Features and Details

Paromomycin Sulfate

SYNONYMS: Paromomycin sulfate salt
CAS: # 1263-89-4
MOLECULAR FORMULA: C23H45N5O14·×H2SO4·×H2O
MOLECULAR WEIGHT: 713.706 g/mol
BEILSTEIN REGISTRY No.: 5715182
EC No: 215-031-7
MDL No: MFCD00079278
SKU 02156056-CF Categories , , Tag

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PRODUCT DESCRIPTION

Paromomycin Sulfate Application Notes Paromomycin is a broad spectrum aminoglycoside antibiotic produced by Streptomyces rimosus var. paromomycinus. It has in vitro and in vivo activity similar to neomycin. It is effective against Gram-negative bacteria, Gram-positive bacteria, some protozoan species, and limited antihelminth.It is used to study bacterial protein synthesis at the level of 16S ribosomal RNA and 30S ribosome assembly. Paromomycin is used to study cytosine-cytosine (CC) mismatch-containing RNA molecules and is used to inhibit Cryptosporidium infection of a human enterocyte cell line. Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. Key Applications Antibiotic
SPECIFICATIONS
SKU: 02156056-CF
Base Catalog Number: 156056
Alternate Names: Paromomycin sulfate salt
Beilstein Registration No : 5715182
Biochemical Physiological Actions : Paromomycin inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and leads to cell death.
CAS : # 1263-89-4
EC No : 215-031-7
Format : Powder
MDL No : MFCD00079278
Molecular Formula : C23H45N5O14·×H2SO4·×H2O
Molecular Weight : 713.706 g/mol
Potency : >675 µg/mg
Purity : >97%
RTECS No : WK2320000
Typical Working Concentration : DILUTION RECCOMENDATIONS: 1:100 - 1:400 for Tissue Staining 1:250 - 1:1,000 for Immuno Blotting 1:1,000 - 1:4,000 for ELISA/FIA

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