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Penicillin G, sodium salt, USP phytopure
Key Features and Details
Number: 69-57-8
SYNONYMS: Benzylpenicillin sodium salt
CAS: #
69-57-8
MOLECULAR FORMULA: C
16H17N2O4Sna
MOLECULAR WEIGHT: 356.40
BEILSTEIN REGISTRY No.: 3834217
EC No: 200-710-2
MDL No: MFCD00069666
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PRODUCT DESCRIPTION
A semi-synthetic, broad-spectrum ß-lactam penicillin antibiotic with bactericidal activity against gram-positive bacteria. It inhibits bacterial cell wall synthesis by disrupting peptidylglycan cross-linking.
Application Notes
Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It has been used to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility and in cell culture both alone and combined with streptomycin and other antibiotics.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Antibiotic
SPECIFICATIONS
SKU: 02194537-CF
Base Catalog Number: 194537
Alternate Names: Benzylpenicillin sodium salt
Beilstein Registration No
: 3834217
Biochemical Physiological Actions
: Mode of Action: The ß-lactam moiety (functional group) of penicillin G binds to the enzyme (DD-transpeptidase) that links the peptidoglycan molecules in bacteria. The enzymes that hydrolyze the peptidoglycan cross-links continue to function, which weakens the cell wall of the bacterium, it causes cytolysis(death due to osmotic pressure) in Bactria. Antimicrobial spectrum: Gram-positive bacteria.
CAS
: #
69-57-8
Density
: 1.41 (NTP, 1992)
EC No
: 200-710-2
Format
: Powder
Grade
: USP
Hazard Statements
: H317-H334
MDL No
: MFCD00069666
Melting Point
: 408 to 414° F (decomposes) (NTP, 1992)
Molecular Formula
: C
16H17N2O4Sna
Molecular Weight
: 356.40
Potency
: >1500 u/mg
PPE
: Dust mask, Eyeshields, Faceshields, Gloves
RTECS No
: XH9800000
Safety Symbol
: GHS08
Solubility
: 50 to 100 mg/mL at 77° F (NTP, 1992)
Sterilization of Solutions
: Solutions should be filter sterilized. Store in small aliquots at appropriate temperature until use.
Typical Working Concentration
: For Gram Positive Bacteria=105 U/L
