Prostaglandin E2, ?-irradiated, =99%, 1 mg
Key Features and Details
Prostaglandin E2
SYNONYMS: [5Z,11a,13E,15S]-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; PGE2; Dinoprostone
CAS: #
363-24-6
MOLECULAR FORMULA: C20H32O5
MOLECULAR WEIGHT: 352.471 g/mol
BEILSTEIN REGISTRY No.: 4709356
EC No: 206-656-6
MDL No: MFCD00077861
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PRODUCT DESCRIPTION
Prostaglandin E2
Application Notes
Prostaglandin E2 is use in cell culture applications for the study of prostaglandin regulated cell signaling and gene regulation.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Study of prostaglandin regulated cell signaling and gene regulation
SPECIFICATIONS
SKU: 0219457601
Base Catalog Number: 19457601
Alternate Names: [5Z,11a,13E,15S]-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; PGE2; Dinoprostone
Beilstein Registration No
: 4709356
Biochemical Physiological Actions
: Most biologically active prostaglandin. PGE2 induces cervical ripening and parturition; mediates bradykinin-induced vasodilation; regulates adenylyl cyclase. Tumor cells that over-express cyclooxygenase 2 display increased invasiveness, angiogenesis, and resistance to apoptosis that may be due to the PGE2-induced expression of angiogenic factors and stabilization of the anti-apoptotic protein, survivin.The effect of PGE2 on the immune system is mixed. It inhibits T cell activation in vitro, suggesting it is an immunosuppressant. However, in vivo, it appears to effect expansion of the Th17 subset and differentiation of the Th1 subset of T helper cells, marking it as an immunoactivator.
CAS
: #
363-24-6
EC No
: 206-656-6
Format
: Solid
Grade
: ?-irradiated
Hazard Statements
: H302-H360
MDL No
: MFCD00077861
Melting Point
: 67 °C
Molecular Formula
: C20H32O5
Molecular Weight
: 352.471 g/mol
PPE
: Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator cartridge,respirator filter
Purity
: =99%
RTECS No
: UK8000000
Safety Symbol
: GHS07, GHS08
Solubility
: Water Solubility58.1 mg/L
Sterility
: ?-Irradiated
