Prostaglandin E2, ?-irradiated, =99%

Key Features and Details

Prostaglandin E2

SYNONYMS: 5Z,11a,13E,15S]-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; Dinoprostone; PGE2
CAS: # 363-24-6
MOLECULAR FORMULA: C20H32O5
MOLECULAR WEIGHT: 352.471 g/mol
BEILSTEIN REGISTRY No.: 4709356
EC No: 206-656-6
MDL No: MFCD00077861
SKU 02195461-CF Categories , , , Tag

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PRODUCT DESCRIPTION

Prostaglandin E2 Application Notes Prostaglandin E2 induces cervical ripening and parturition; mediates bradykinin-induced vasodilation. Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. Key Applications Induces cervical ripening and parturition
SPECIFICATIONS
SKU: 02195461-CF
Base Catalog Number: 195461
Alternate Names: 5Z,11a,13E,15S]-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; Dinoprostone; PGE2
Beilstein Registration No : 4709356
Biochemical Physiological Actions : Most biologically active prostaglandin. PGE2 induces cervical ripening and parturition; mediates bradykinin-induced vasodilation; regulates adenylyl cyclase. Tumor cells that over-express cyclooxygenase 2 display increased invasiveness, angiogenesis, and resistance to apoptosis that may be due to the PGE2-induced expression of angiogenic factors and stabilization of the anti-apoptotic protein, survivin.The effect of PGE2 on the immune system is mixed. It inhibits T cell activation in vitro, suggesting it is an immunosuppressant. However, in vivo, it appears to effect expansion of the Th17 subset and differentiation of the Th1 subset of T helper cells, marking it as an immunoactivator.
CAS : # 363-24-6
EC No : 206-656-6
Format : Powder
Hazard Statements : H302-H360
MDL No : MFCD00077861
Melting Point : 67 °C
Molecular Formula : C20H32O5
Molecular Weight : 352.471 g/mol
PPE : Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator filter, respirator cartridges
Purity : =99%
RTECS No : UK8000000
Safety Symbol : GHS07, GHS08
Solubility : Water Solubility58.1 mg/L
Source : Synthetic

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