No products in the cart.
Sorbitol dehydrogenase, 5 mg
Key Features and Details
Sorbitol Dehydrogenase
SYNONYMS: L-Iditol dehydrogenase; Polyol dehydrogenase; L-Iditol: NAD+ 5-oxidoreductase; EC 1.1.1.14; SDH
CAS: #
9028-21-1
MDL No: MFCD00131994
You need to register an account with us
to be able to place an order, Click to Register.
PRODUCT DESCRIPTION
Sorbitol Dehydrogenase
Application Notes
Sorbitol dehydrogenase has been used in a study to investigate osmotic stress induced oxidative damage as a possible mechanism of cataract formation in diabetes.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Cabrohydrate metabolism
SPECIFICATIONS
SKU: 0215664205
Base Catalog Number: 15664205
Alternate Names: L-Iditol dehydrogenase; Polyol dehydrogenase; L-Iditol: NAD+ 5-oxidoreductase; EC 1.1.1.14; SDH
Biochemical Physiological Actions
: Activity of sorbitol dehydrogenase increases in diabetic animals.
CAS
: #
9028-21-1
Format
: Powder
Hazard Statements
: H317
MDL No
: MFCD00131994
PPE
: Eyeshields, Gloves, respirator filter
Source
: Sheep Liver
Specific Activity
: =20 u/mg protein
Specificity
: Reduces L-iditol to L-sorbose. Also acts on D-glucitol and other closely related sugar alcohols. Allows the reduction of ketones to polyols. The reduction of D-fructose is favored. However; alkaline pH shifts the equilibrium in favor of sorbitol oxidation. SDH does not oxidize erythritol; D- or L-arabitol; D-iditol; D-mannitol or inositol. It will not reduce D-tagatose; D-mannoheptulose; D-glucose; DL-glyceraldehyde; pyruvate; 2-oxolutarate or acetaldehyde.
Unit Definition
: One unit will convert 1.0 umole of D-fructose to D-sorbitol per minute at pH 7.6 at 25 °C.
