No products in the cart.
Superoxide dismutase, =3500 U/mg solid
Key Features and Details
Superoxide dismutases are enzymes that catalyze the dismutation of superoxide into oxygen and hydrogen peroxide. Thus, they are an important antioxidant defense in nearly all cells exposed to oxygen.Superoxide dismutases are a group of low molecular weight metalloproteins present in all aerobic cells of plants, animals and micro-organisms. They provide protection against damaging reactions with the superoxide radical anion (O2-) by catalyzing its disproportionation into oxygen and hydrogen peroxide.
SYNONYMS: SOD; Superoxide: superoxide oxidoreductase
CAS: #
9054-89-1
MOLECULAR WEIGHT: ~32;500 Daltons (Lit.)
EC No: 232-943-0
MDL No: MFCD00132404
You need to register an account with us
to be able to place an order, Click to Register.
PRODUCT DESCRIPTION
Superoxide dismutases are enzymes that catalyze the dismutation of superoxide into oxygen and hydrogen peroxide. Thus, they are an important antioxidant defense in nearly all cells exposed to oxygen.Superoxide dismutases are a group of low molecular weight metalloproteins present in all aerobic cells of plants, animals and micro-organisms. They provide protection against damaging reactions with the superoxide radical anion (O2-) by catalyzing its disproportionation into oxygen and hydrogen peroxide.
Application Notes
Superoxide Dismutase plays a critical role in the defense of cells against the toxic effects of oxygen radicals.Superoxide dismutase from bovine erythrocytes has been used in a study to assess a kinetic model of radiation-induced inactivation of superoxide dismutase in nitrous oxide-saturated solutions. Superoxide dismutase from bovine erythrocytes has also been used in a study to investigate the possible participation of superoxide anion in the intestinal tryptophan 2,3-dioxygenase reaction.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Catalyst in dismutation of superoxide
SPECIFICATIONS
SKU: 02190117-CF
Base Catalog Number: 190117
Alternate Names: SOD; Superoxide: superoxide oxidoreductase
Biochemical Physiological Actions
: Superoxide dismutase catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. It competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice.
CAS
: #
9054-89-1
Concentration
: =0.900 mg protein/mg solid
EC No
: 232-943-0
Extinction Coefficient
: 2.64 (1%/280) (Lit.)
Format
: Lyophilized salt-free powder
Isoelectric Point
: 4.95 (Lit.)
MDL No
: MFCD00132404
Molecular Weight
: ~32;500 Daltons (Lit.)
PPE
: Eyeshields, Gloves, Repirator Filter.
Solubility
: Dissolves readily at 5mg/mL in 0.05M potassium phosphate/0.1mM EDTA pH 7.8, to give a clear slightly blue solution.
Source
: Bovine Erythrocytes
Specific Activity
: =3500 u/mg solid
Unit Definition
: That amount of enzyme causing a 50% inhibition in the rate of assay based on the method of McCord, J.M. and Fridovich, (1969), J. Biol. Chem., 1, 6049.
