NucleoSpin miRNA is suitable for simultaneous isolation of small RNA (<200 nt, e.g., miRNA, pre-miRNA, tRNA, 5S RNA), large RNA (>200 nt, e.g., mRNA, 18S rRNA, 28S rRNA, pri-miRNA), and protein in three separate fractions from a large variety of sample materials. NucleoSpin miRNA Plasma is designed for the isolation of small RNA from plasma or serum for cancer research. Typical downstream applications are real-time qRT-PCR and chip hybridizations.