SulfoBiotics- SSP4

Description

It has become obvious that there are a lot of molecules containing sulfane sulfurs, such as persulfides and polysulfides, in living organisms. These molecular species are involved in production, storage and release of hydrogen sulfide, which is recognized as an important physiological mediator. Furthermore, recent studies reveal that persulfides and polysulfides may control intracellular signal transduction through s-sulfhydration of proteins.

SSP4 (Sulfane Sulfur Probe 4) is a novel fluorescent probe to detect sulfane sulfurs selectively. SSP4 itself is non-fluorescent, but it emits strong green fluorescence when it reacts with sulfane sulfurs. Thus, SSP4 enables highly sensitive fluorescence detection and imaging of sulfane sulfurs.