Lipi-Blue

Description

Lipid droplets (LDs) are composed of neutral lipids such as triacylglycerol & cholesteryl ester that are surrounded by phospholipid monolayers and are seen ubiquitously, not only in adipocytes. LDs were originally thought to serve as a lipid storage unit, until a recent study showing that LDs play an important role in regulating lipid metabolism, autophagy and cellular senescence. Therefore, LDs have gained great attention as an important tool to elucidate the mechanisms of their formation, growth, fusion, and retraction.

The Lipi dyes have greatly improved the issues (specificity, color options, and retention) of existing lipid droplet staining reagents, such as Oil Red O and Nile Red, and are small molecules which emit strong fluorescence in a hydrophobic environment such as in LDs.