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Cell Membrane Staining

The plasma membrane (PM) consists of a lipid bilayer separating the intracellular environment from the extracellular space. Consequently, the PM plays a central role in many cell behaviors, such as cell migration, cell stretching, and signaling cascades. Additionally, PM dysfunction is an important biomarker because it is related to the cell status and is linked to many diseases.
Dojindo's PlasMem Bright dyes overcome the limitations of existing membrane dyes, which have short retention in the PM and require a special solution for dilution due to low water solubility. PlasMem Bright dyes are designed to stain PMs for over a day, and are more water-soluble compared with other commercially available dyes, so they can be diluted with culture medium. The PlasMem Bright dyes offer two different color options (green and red) and are provided as ready-to-use DMSO solutions. A working solution can be prepared easily via a single dilution step using growth medium or HBSS.
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